If WickedWhims is installed, sims can pay dealers for drugs with sex. Drugs can form addictions (which will result in an addiction moodlet for the affected sim), and repeated use of drugs in a short period of time can result in a sim's death by overdose. Cannabis seeds are included for gardening (incorrectly categorized in Indoor Plants, rather than with the other seed packets in Outdoor Activities), as well as rolling papers, weed curing jars, and bongs.

The only drugs available in buy mode are cocaine, amphetamine, MDMA, and tobacco. The drugs are acquired in differing and semi-realistic ways, with not all being available for purchase in buy mode. The mod also includes edits to mixology that adds new drink recipes, as well as the ability for sims to become drunk, and even alcoholics. The list includes cannabis (weed), tobacco, cocaine, amphetamine, shrooms, MDMA, ayahuasca, xanax, lean, adderall, LSD, and steroids. The most prominent feature of the mod is its range of drugs for sims to experiment with.